Amgen is a multinational biopharmaceutical company headquartered in Thousand Oaks, California. Located in the Conejo Valley, Amgen is the world's largest independent biotechnology firm. Epogen and Neupogen were the two most successful biopharmaceutical products at the time of their respective releases. Amgen is the largest employer in Thousand Oaks and second only to the United States Navy in terms of number of people employed in Ventura County. BusinessWeek ranked Amgen first on the S&P 500 for being one of the most "future-oriented" of those five hundred corporations. BusinessWeek... ostensibly calculated the ratio of research and development spending, combined with capital spending, to total outlays; Amgen had the fourth highest ratio, at 506:1000. The company employs approximately 17,000 staff members. Its products include Epogen, Aranesp, Enbrel, Kineret, Neulasta, Neupogen, Sensipar/Mimpara, Nplate, Vectibix, Prolia and XGEVA. Amgen has several collaborative arrangement with Pfizer Inc, GlaxoSmithKline, Takeda Pharmaceutical Company, Kyowa Hakko Kirin, Daiichi Sankyo and Array BioPharma.
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| NASDAQ symbol: | AMGN |
| Founded: | 1980 |
| Headquarters: | Thousand Oaks, California |
| Legal structure: | Publicly listed company, Public company |
| Annual revenue: | $15,003,000,000 |
| Net income: | $4,196,000,000 |
| Operating income: | $5,214,000,000 |
| Market cap: | $51,000,000,000 |
| Employees: | 15,000 |
| Industries: | Biotechnology, Biological Product (except Diagnostic) Manufacturing |