| Rank | Game | Copies Sold | |
|---|
| 1 |
| Super Mario World | 20,000,000 | |
| 2 |
| Donkey Kong Country | 8,000,000 | |
| 3 |
| Super Mario Kart | 8,000,000 | |
| 4 |
| Street Fighter II | 6,300,000 | |
| 5 |
| The Legend of Zelda: A Link to the Past | 4,610,000 | |
| 6 |
| Donkey Kong Country 2: Diddy's Kong Quest | 4,370,000 | |
| 7 |
| Street Fighter II Turbo | 4,100,000 | |
| 8 |
| Star Fox | 4,000,000 | |
| 9 |
| Super Mario World 2: Yoshi's Island | 4,000,000 | |
| 10 |
| Donkey Kong Country 3: Dixie Kong's Double Trouble! | 2,890,000 | |
| 11 |
| Chrono Trigger | 2,700,000 | |
| 12 |
| Super Street Fighter II | 2,000,000 | |
| 13 |
| Secret of Mana | 1,830,000 | |
| 14 |
| Aladdin | 1,750,000 | |
| 15 |
| Mortal Kombat II | 1,510,000 | |
| 16 |
| Romancing SaGa 2 | 1,490,000 | |
| 17 |
| Final Fight | 1,480,000 | |
| 18 |
| Killer Instinct | 1,330,000 | |
| 19 |
| Romancing SaGa | 1,320,000 | |
| 20 |
| The Lion King | 1,270,000 | |
| 21 |
| Mortal Kombat 3 | 1,220,000 | |
| 22 |
| NBA Jam | 1,220,000 | |
| 23 |
| Disney's Magical Quest | 1,210,000 | |
| 24 |
| Mega Man X | 1,160,000 | |
| 25 |
| Super Ghouls 'n Ghosts | 1,090,000 | |
| 26 |
| Final Fight 2 | 1,030,000 | |
| 27 |
| Casper | 1,000,000 | |