Human Genome Project

Great Britain or Britain is an island situated to the northwest of Continental Europe. It is the ninth largest island in the world, and the largest... European island, as well as the largest of the British Isles. With a population of about 60.0 million people in mid-2009, it is the third most populous island in the world, after Java and Honshū. Great Britain is surrounded by over 1,000 smaller islands and islets. The island of Ireland lies to its west. Politically, Great Britain may also refer to the island itself together with a number of surrounding islands which comprise the territory of England, Scotland and Wales. All of the island is territory of the sovereign state of the United Kingdom of Great Britain and Northern Ireland, and most of the United Kingdom's territory is in Great Britain. Most of England, Scotland, and Wales are on the island of Great Britain, as are their respective capital cities: London, Edinburgh, and Cardiff. The Kingdom of Great Britain resulted from the political union of the kingdoms of England and Scotland with the Acts of Union 1707 on 1 May 1707 under Queen Anne.
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Canada is a North American country consisting of ten provinces and three territories. Located in the northern part of the continent, it extends from... the Atlantic Ocean in the east to the Pacific Ocean in the west, and northward into the Arctic Ocean. Spanning over 9.9 million square kilometres, Canada is the world's second-largest country by total area, and its common border with the United States is the longest land border in the world. The land that is now Canada has been inhabited for millennia by various groups of Aboriginal peoples. Beginning in the late 15th century, British and French expeditions explored, and later settled, along the region's Atlantic coast. France ceded nearly all of its colonies in North America in 1763 after the Seven Years' War. In 1867, with the union of three British North American colonies through Confederation, Canada was formed as a federal dominion of four provinces. This began an accretion of provinces and territories and a process of increasing autonomy from the United Kingdom.
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New Zealand is an island country in the south-western Pacific Ocean comprising two main landmasses and numerous smaller islands. The country is... situated some 1,500 kilometres east of Australia across the Tasman Sea, and roughly 1,000 kilometres south of the Pacific island nations of New Caledonia, Fiji, and Tonga. Because of its remoteness, it was one of the last lands to be settled by humans. During its long isolation New Zealand developed a distinctive fauna dominated by birds, many of which became extinct after the arrival of humans and introduced mammals. With a mild maritime climate, the land was mostly covered in forest. The country's varied topography and its sharp mountain peaks owe much to the uplift of land and volcanic eruptions caused by the Pacific and Indo-Australian Plates clashing underfoot. Polynesians settled New Zealand in 1250–1300 AD and developed a distinctive Māori culture, and Europeans first made contact in 1642 AD. The introduction of potatoes and muskets triggered upheaval among Māori early during the 19th century, which led to the inter-tribal Musket Wars.
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In genetics, shotgun sequencing, also known as shotgun cloning, is a method used for sequencing long DNA strands. It is named by analogy with the... rapidly-expanding, quasi-random firing pattern of a shotgun. Since the chain termination method of DNA sequencing can only be used for fairly short strands , longer sequences must be subdivided into smaller fragments, and subsequently re-assembled to give the overall sequence. Two principal methods are used for this: chromosome walking, which progresses through the entire strand, piece by piece, and shotgun sequencing, which is a faster but more complex process, and uses random fragments. In shotgun sequencing, DNA is broken up randomly into numerous small segments, which are sequenced using the chain termination method to obtain reads. Multiple overlapping reads for the target DNA are obtained by performing several rounds of this fragmentation and sequencing. Computer programs then use the overlapping ends of different reads to assemble them into a continuous sequence. Shotgun sequencing was one of the precursor technologies that was responsible for enabling full genome sequencing.
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