Middlesex County, in the U.S. state of Massachusetts, is the twenty-third most populous county in the United States and the most populous county in New England. As of 2010, the population was 1,503,085, making it more populous than the entire state of Maine. The center of population of Massachusetts is in Natick, Middlesex County. For administrative purposes the county held two regions, Middlesex-North with county seat in Lowell, and Middlesex-South with county seat in Cambridge. The county government was abolished in 1997, but the county boundaries continue to describe a state district for... court jurisdictions and for other administrative purposes, such as an indicator for elections. As of 2006, Middlesex County was tenth in the United States on the list of most millionaires per county. The county was created by the Massachusetts General Court on May 10, 1643, when it was ordered "that the whole plantation within this jurisdiction be divided into four sheires". Middlesex initially contained Charlestown, Cambridge, Watertown, Sudbury, Concord, Woburn, Medford, and Reading.
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