O'Fallon is a suburban city along Interstate 70 and Interstate 64 between Lake St. Louis and St. Peters in Saint Charles County, Missouri. It is part of the St. Louis Metropolitan Statistical Area. As of the 2010 census population of 79,329, it is the seventh largest city in the state and the largest in St. Charles County. In 2006 Money Magazine named O'Fallon as one of its "Best 100 Places to Live." Money Magazine also ranked O'Fallon 68 out of 100 in 2008 and 26 out of 100 in 2010 As noted above, O'Fallon, along with its namesake in St. Clair County, Illinois is part of the St. Louis... Metropolitan Statistical Area. This makes O'Fallon one of the few pairs of like-named municipalities to be part of the same MSA. After the War of 1812, there was a westward flow of migration through the present-day St. Charles County on the Booneslick Trail . During the 1830s, many German settlers came to the O'Fallon area inspired by Gottfried Duden's Republic of the Western States of North America. The report was based on his account of living in St. Charles.
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| County: | St. Charles County |
| State: | Missouri |
| Country: | United States of America |
| Population: | 76,819 |
| Area: | 22.5 sq. mi. |
| Time zone: | Central Time zone |
| Also known as: | O'Fallon, Missouri, St. Charles County / O'Fallon city |