Splice is a 2009 Canadian/French science fiction horror film directed by Vincenzo Natali and starring Adrien Brody and Sarah Polley. The story concerns experiments in genetic engineering being done by a young scientist couple who attempt to introduce human DNA into their work of splicing animal genes. Genetic engineers Clive Nicoli and Elsa Kast hope to achieve fame by successfully splicing together the DNA of different animals to create new hybrid animals for medical use. They have just created the second in a pair of identical hybrids; the new male specimen, Fred, is intended as a mate... for the original specimen, a female called Ginger. After their success, Clive and Elsa want to use human DNA to create a hybrid that could revolutionize science and medicine, but are forbidden by the pharmaceutical company that funds their research, N.E.R.D. , instead mandating that their department be re-organized to focus on finding and extracting certain proteins from the creatures they have already created. Secretly, Clive and Elsa conduct their own experiments, blending human DNA with that of other animals.
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| Release date: | October 6, 2009 |
| Directed by: | Vincenzo Natali |
| Rated: |  |
| Runtime: | 107 Minutes |
| Producer: | Steven Hoban |
| Editor: | Michele Conroy |
| Music by: | Cyrille Aufort |
| Cinematography: | Tetsuo Nagata |
| Screenplay by: | Vincenzo Natali, Antoinette Terry Bryant, Doug Taylor |
| Estimated budget: | $26,000,000 |
| Genre: | Science Fiction, Thriller |