Elizabeth Blackburn
Albert Lasker Award for Basic Medical Research
Elizabeth Helen Blackburn, AC, FRS is an Australian-born American biological researcher at the University of California, San Francisco, who studies... the telomere, a structure at the end of chromosomes that protects the chromosome. Blackburn co-discovered telomerase, the enzyme that replenishes the telomere. Blackburn recalls: "Carol had done this experiment, and we sat down, just in the lab, and I remember sort of standing there, and she had this -- we call it a bum. It's an autoradiogram, because there was trace amounts of radioactivity that were used to develop an image of the separated DNA products of what turned out to be the telomerase enzyme reaction. I remember looking at it and just thinking, ‘Ah! This could be very big. This looks just right.’ It had a pattern to it. There was a regularity to it. There was something that was not just sort of garbage there, and that was really kind of coming through, even though we look back at it now, we'd say, technically, there was this, that and the other, but it was a pattern shining through, and it just had this sort of sense, ‘Ah! There's something real here.
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